Glutamic acid - wehewehe, waiwai, kuhikuhi

ʻO ka glutamic (glutamic) acid kekahi o nā ʻano o nā amino acid, ʻo ia ka mea nui o ka aneane o nā protein i ke kino. Pili ia i ka papa o nā amino acid "excitatory", ʻo ia hoʻi. ka paipai ʻana i ka lawe ʻana o nā pulupulu nerve mai ke kikowaena a i ka ʻōnaehana nūnū peripheral. I ke kino, ʻo kona kukuna he 25% o ka huina o kēia mau mea.

ʻAkika amino hana

Loiloi ʻia ʻo Glutamic acid no ke komo ʻana i ka synthesist o nā mea he nui o nā kumuwaiwai (histamine, serotonin, folic acid). Ma muli o kāna detoxifying waiwai, kōkua kēia amino acid i ka hoʻopau ʻana i ka hana o ka amonia a hemo iā ia mai ke kino. Ma muli o ka mea he ʻāpana hoʻohui o nā protein, pili ia i ka metabolism ikehu, mea nui ka waikawa no ka poʻe e hana nui nei i nā haʻuki.

ʻO ka hana nui o ka glutamic acid ka mea e hōʻeleu i ka lawe ʻana o nā impulses nerve ma muli o ka hopena excitatory ma nā neurons. I ka nui o ka nui, hoʻomaikaʻi ia i ka hana o ka lolo ma ka wikiwiki ʻana i ka wikiwiki o nā hana noʻonoʻo. Akā me ka nui o ka noʻonoʻo ʻana, ʻike nā hunaola nerve i ka pīhoihoi nui, kahi e hiki ai i ko lākou hōʻino a me ka make. Pale ʻia nā neurons e neuroglia - hiki iā lākou ke komo i nā mole mole glutamic me ka waiho ʻole ʻia i loko o ka wahi intercellular. I mea e hōʻalo ai i kahi overdose, pono ia e kaohi i ka lāʻau a ʻaʻole ʻoi aku ma mua o ia.

Hoʻomaikaʻi ka Glutamic acid i ka permeability o ka potassium i loko o nā hunaola o nā olonā, e like me nā olonā o ka puʻuwai puʻuwai, e hoʻopili ana i kāna hana. Hoʻoulu ia i ka hiki ke ola hou o nā kumulāʻau a pale i ka hanana o hypoxia.

ʻImi i nā huahana

Loaʻa i ke kino ka glutamic acid mai ka meaʻai. ʻIke ʻia i kahi kiʻekiʻe kiʻekiʻe i nā cereal, nā nati (ʻoi aku i nā pī), i nā legume, nā ʻanoʻano, nā hua waiū, nā ʻiʻo like ʻole, nā palaoa a me nā gluten.

I kahi ʻōpio, kino olakino, lawa ka waikawa glutamic mai ka meaʻai no ka hana maʻamau. Akā me ka makahiki, i ke alo o nā maʻi mau, a me nā haʻuki ikaika hoʻi, e emi ana kāna ʻike a koi pinepine ke kino i nā kumuwaiwai hou aʻe o kēia mea.

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Nā hōʻike no ka hoʻohana

Pono ka hana o ka glutamic acid no ka pale ʻana a me ka mālama ʻana i nā ʻano maʻi like ʻole o ka ʻōnaehana makaʻu. Kauoha ʻia ia no nā ʻano palupalu o ka epilepsy, nā maʻi noʻonoʻo, nāwaliwali o ka hopohopo, neuropathy, kaumaha, a me ka hoʻopau ʻana i nā pilikia ma hope o ka meningitis a me ka encephalitis. I nā pediatrics, hoʻohana ʻia ka glutamic acid i loko o ka kompleks therapy no ka palsy pēpē pēpē, ka maʻi o Down, ka noʻonoʻo noʻonoʻo, a me ka poliomyelitis.

No ka hoʻoikaika kino koʻikoʻi me ka hoʻohana ʻana i ka ikehu kiʻekiʻe, hoʻohana ʻia ia ma ke ʻano he mea hoʻihoʻi.

Nā ʻōkuhi no ka hoʻohana

Lawe nā mākua i hoʻokahi gram ma mua o ʻekolu mau manawa o ka lā. Ka mahele lāʻau no nā keiki pili i ka makahiki:

• Hiki i hoʻokahi makahiki - 100 mg.
• Hiki i 2 mau makahiki - 150 mg.
• 3-4 mau makahiki - 250 mg.
• 5-6 mau makahiki - 400 mg.
• 7-9 mau makahiki - 500-1000 mg.
• 10 mau makahiki a ʻoi aku - 1000 mg.

Glutamic acid i nā haʻuki

ʻO ka glutamic acid kekahi o nā mea o ka meaʻai haʻuki. Mahalo iā ia, hana ʻia nā kumuwaiwai amino ʻē aʻe he nui a me nā kumumea. ʻO kēia ke kumu o ka loaʻa ʻole o kekahi ʻano o nā mea i loko o ke kino, hiki iā lākou ke synthesize ʻia mai nā poʻe ʻē aʻe, kiʻekiʻe ka ʻike o kēia wā. Hoʻohana nui ʻia kēia waiwai e nā poʻe haʻuki ke kiʻekiʻe loa ke kekele o ka ukana, a ua loaʻa ka protein liʻiliʻi mai ka meaʻai. I kēia hihia, pili ka glutamic acid i ke kaʻina hana o ka hāʻawi hou ʻana o ka nitrogenous a kōkua i ka hoʻohana ʻana i nā protein i loko o ka nui o ka nui o ka hanana o nā ʻōlio kūloko no ke kūkulu ʻana a me ka hoʻoponopono ʻana o nā hunaola olonā.

ʻO ka nui o ka ukana a ka mea haʻuki, ʻo ka nui o nā mea ʻona i hana ʻia i loko o kona kino, e like me ka amonia weliweli loa. Ma muli o kona hiki ke hoʻopili i nā mole amonia iā ia iho, lawe ka acid glutamic iā ia mai ke kino, e pale ana i nā hopena maikaʻi ʻole.

Hiki i ka amino acid ke hōʻemi i ka hana ʻana o ka lactate, ka mea e hōʻeha ai i ka ʻeha ma ka hoʻoikaika kino i ka hoʻoikaika kino.

Hoʻohui ʻia, hoʻololi koke ʻia ka glutamic acid i glucose, i hiki ke hemahema i nā mea pāʻani i ka wā hoʻoikaika kino.

Nā Kūʻai Kūʻai

ʻAʻole pono e hoʻohui ʻia ka glutamic acid i ka papaʻai ke:

• nā maʻi o nā puʻupaʻa a me ke ake;
• peptic ulcer;
• kuni;
• kiʻekiʻe excitability;
• hyperactivity;
• ke kaumaha nui;
• nā maʻi o nā lālā hematopoietic.

Nā hopena ʻaoʻao

• Haunaele hiamoe.
• Dermatitis.
• Nā hopena āpau.
• Opu hoʻowahāwahā.
• Hoʻoemi i nā pae hemoglobin.
• Hoʻonui i ka pīhoihoi.

ʻO ka glutamic acid a me ka glutamine

ʻO nā inoa o kēia mau mea ʻelua i like loa, akā he like a like ka waiwai a me nā hopena? Aʻole naʻe. Hoʻohui ʻia ka Glutamic acid i glutamine, ʻo ia ke kumu o ka ikehu a me kahi mea nui o nā hunaola, nā ʻili a me nā mea hoʻopili. Inā ʻaʻole lawa ka glutamic acid i loko o ke kino, ʻaʻole kū ka synthesist o glutamine i ka nui i koi ʻia, a hoʻomaka ka hope i nā mea ʻē aʻe, no ka laʻana, mai nā protein. ʻO kēia ke kumu o ka loaʻa ʻole o ka protein i loko o nā hunaola, e hopena ai i ka ʻili a me ka emi ʻana o ka nui o nā mākala.

Inā mākou e kamaʻilio e pili ana i nā ʻano ʻokoʻa o ka glutamine a me ka glutamic acid, a laila hiki iā mākou ke ʻike i nā ʻokoʻa aʻe:

1. Loaʻa i ka glutamine kahi mole mole nitrogen i loko o kāna ʻano kemika a loaʻa kahi hopena hou, hoʻonui i ka nui o nā mākala, ʻoiai ʻaʻohe nitrogen a loaʻa kahi hopena stimulate i ka glutamic acid;
2. Kūʻai ʻia ka glutamic acid i nā hale kūʻai lāʻau wale nō i ka pila pila, ʻoiai hiki ke kūʻai ʻia ka glutamine i ka pauka, papa a me nā ʻano capsule;
3. pili ke ana o ka glutamine i ke kaupaona o ke kino a lawe ʻia ma ka helu o 0.15 g a 0.25 g no kg kg o ke kaupaona, a lawe ʻia ka glutamic acid 1 g i kēlā me kēia lā;
4. ʻo ka pahuhopu nui o ka glutamic acid ʻo ia ka ʻōnaehana hopohopo kikowaena me kāna mau pono āpau, a he hopena maikaʻi kā ka glutamine ʻaʻole wale ma ka ʻōnaehana ʻōnaehana - hana nui ia i ka hoʻihoʻi hou ʻana o nā mākala a me nā pūnaewele hoʻopili hoʻopili, paipai i ka haʻihaʻi momona a pale i ka catabolism.

I loko nō o nā ʻokoʻa i helu ʻia ma luna, pili mau kēia mau mea i kekahi i kekahi - ʻo ka lawe ʻana i ka waikawa glutamic e hoʻonui ai i ka paʻa o ka glutamine.

E nānā i ka wikiō: Glutamate Dehydrogenase: Catabolism of Glutamate (Mei 2025).