ʻO ka Vitamins kahi hui nui o nā meaola kūlohelohe o nā ʻano ʻano like ʻole, akā hui pū ʻia e hoʻokahi hiʻohiʻona maʻamau - pono i ke kino e loaʻa i kēia mau mea me ka meaʻai, ʻoiai ʻaʻole hiki ke hana i kā lākou kūʻokoʻa kūʻokoʻa. Hoʻopili kēia mau mea hoʻohui i ka folic acid - ka huaʻai B9, folacin, kahi e hana nui i nā hana metabolic, no laila, kona hemahema a i ʻole ke alakaʻi nui ʻana i nā hanana pathological. Hoʻohana ʻia ʻo Folic acid i ka hana olakino, a me ka lāʻau haʻuki.
Overview o ka wikamina
No ka manawa mua, ua ʻike ʻia ka wikamina ma ke aʻo ʻana o nā microorganism. Ua ʻike ʻo Snell lāua ʻo Peterson i ka pono o ka bacteria i kekahi ʻano hui e ulu a hānau hou, i loaʻa i ka milo. Ua kapa ʻia ka Vitamin B9 acid folic no ka mea pili ʻia kāna ʻike me kahi mea kanu ʻōmaʻomaʻo: "folium" - kahi lau.
ʻO ka hui kahi ʻāpana o kahi helu o nā enzyme, no laila ke komo nei i nā hopena metabolic. ʻO kahi hana nui a ka folic acid e hoʻoponopono i ka ulu a me ka hoʻomohala ʻana o ka cell. Ma ke ʻano he coenzyme, komo ka hui i ka synthesite o nā molaki DNA, ʻo ia hoʻi kāu thymidine. Ua hōʻoia ʻia kēia hana ma ke ʻano o ka hoʻonui ʻana o ka maʻi bacteria i ka hoʻohui ʻia ʻana o ka waikawa i ka meahana moʻomeheu.
He hopena maikaʻi ka Folic acid i ka hana o ka iwi iwi, ʻo ka hana nui a hematopoiesis. Loaʻa kēia i ka ʻoiaʻiʻo o ka hana ʻana o nā mea hou o ke koko ma muli o ka mahele wikiwiki a me ka ulu ʻana o nā hunaola. No ka papa maʻamau o kēia mau kaʻina hana, pono ka vitamini B9, ʻoiai pili ka mea i ka hoʻokumu ʻana o nā nucleotides a me DNA replication.
Hōʻike ka inoa kaulana o ka lāʻau "wahine wahine" i kekahi hana koʻikoʻi - pono ka waikawa folic i kahi nui i ka wā hāpai, no ka mea e hōʻoia i ka mahele maʻamau o nā hunaola fetal a me ko lākou ulu ʻana. Ua hōʻike ʻia kekahi mau noiʻi hoʻokolohua i kahi hui nui o nā wahine postmenopausal me nā pae vitamina o ke koko maʻamau i loaʻa iki i ka maʻi kanesa o ka umauma. No laila, manaʻoʻiʻo ʻia ka pale ʻana o ka folic acid i ka hana ʻana i nā neoplasms malignant.
Hoʻohui ʻia, he hopena maikaʻi kā ka hui ʻana i ka hana o ka digestive tract, paipai i ka lawe ʻana a me ka hana ʻana i nā momona a me nā haʻuki. Mālama ka wikamina i nā hana metabolic o nā hunaola o ka ʻōnaehana hopohopo. He hopena angioprotective ʻo Folic acid, ʻo ia hoʻi, pale ia i nā kīʻaha koko mai nā ʻano ʻino like ʻole, hoʻemi i ka makaʻu o ka hoʻomohala ʻana i nā maʻi puʻuwau coronary a me nā pathologies ʻē aʻe.
ʻO ka Vitamin B9 ma ke ʻano he coenzyme ka mea e hoʻoulu ai i ka serotonin, no laila, no nā maʻi depressive, kuhikuhi nā psychiatrists i kahi lawe paʻakikī o ka papa nui o nā lāʻau a me ka folic acid.
Hoʻohana pinepine ʻia ka wikamina e nā poʻe ʻaleʻale e hoʻonui i ka ulu ʻana o nā mākala, mālama i ka ʻōnaehana ʻōnaehana, a hoʻemi i ka luhi.
Nā Kūlana
Ma muli o ka hiki ʻole i ke kino ke synthesize kūʻokoʻa i ka folic acid, pono ka lawe ʻana i kēlā me kēia lā me ka meaʻai. ʻO nā pēpē hānau hou ma ka awelika pono iā 50 mcg i kēlā me kēia lā, i ka makahiki e piʻi ai ke kiʻi i 70 mcg, e ʻelima - a i 100 mcg. Mai ka 11-12 mau makahiki, pono i kahi keiki 200 mcg. ʻO ka maʻamau no kahi mākua ʻo 400 mcg. Eia kekahi, i ka wā o ka hāpai ʻana, hoʻonui ka pono i 200 mcg, ʻo ia hoʻi, pono i ka wahine 600 mcg, a i ka wā o ka hānai ʻana - 500 mcg.
Nā huahana
I ka makahiki 1920, ua ʻike ʻia ka mālama ʻana i ka papaʻai, ʻo ia hoʻi ka hū a me ke ake, hoola i nā mea maʻi me ka anemia megaloblastic. Ua ʻike pono ʻia kahi noiʻi hou e pili ana i nā meaʻai i piha ka nui o nā folacin:
- nā huaʻai a me kā lākou mau derivatives, ʻo ka hua citrus;
- nā mea kanu - Kupu ʻo Brussels, spinach a me nā meaʻai ʻōmaʻomaʻo me nā kala momona;
- palaʻai;
- nā pī, nā huahana mea kanu mai nā pīni a me nā pī;
- akepaʻa pipi.
Pākuʻi
Hiki ke hāʻawi ʻia i ka lawe ʻana o ka waikawa folic i loko o ke kino e ka lawe ʻana i nā lāʻau lapaʻau loea. Inā ʻaʻohe o kekahi kanaka e hiki ke hahai i ka papaʻai i hoʻonui ʻia me nā meaʻai kiʻekiʻe i ka wikamina B9, paipai nā kauka i ka lawe ʻana i nā lāʻau kō. Hoʻohui ʻia, kuhikuhi ʻia nā lāʻau e komo pū me ka waikawa folic ma ke ʻano he prophylaxis a i ʻole he ʻāpana o kahi lapaʻau ākea no nā maʻi o ka gastrointestinal tract, ka iwi iwi, a i ka wā hāpai. Ma ke ʻano he rula, me ka loaʻa kūpono o ka wikamina, ʻaʻole nānā ʻia nā hopena maikaʻi ʻole. Hōʻike ʻia ka overdose e ka nausea, ka luaʻi, ka ʻeha o ka ʻōpū, ʻono ka hao i ka waha, nā maʻi urinary, ka pīhoihoi, ka hiamoe ʻole, a me nā ʻōuli ʻē aʻe.
Nā hopena o ka nui loa, nele
Ma muli o nā kumu he nui, hiki i ka hypo- a me ka hypervitaminosis i loko o ke kino. Hoʻohālikelike ʻia nā pathologies ʻelua e ka hoʻomohala ʻana i kahi ʻano simptoma kikoʻī, a kū i kahi weliweli i ke kino ma ke ʻano holoʻokoʻa.
ʻAʻole lawa ka nui o ka folacin i ke koko.
- Kū'ē i ke kua o ka wī a lawa ʻole ka nui o nā meaʻai. I ka manawa like, kaupalena ʻia ka lawe ʻana o ka mea e ka mea alimentary, ka hoʻohana maʻamau o greens, nā mea ʻai a me nā huaʻai.
- Ma ke ʻano he hopena o ka mālama ʻana i ka wela i ka meaʻai. I ka hanana i hele mai ka hapa nui o nā meaʻai i ka hana i hana ʻia, hoʻemi ka pae o ka huaʻai B9 i ke koko. ʻO kēia kūlana ma muli o ke kūpaʻa ʻole o ke ʻano o ka folic acid ke hōʻike ʻia i nā mahana, ʻo ia hoʻi, hoʻopau ʻia ka huaora.
- Ma muli o ka uhaki o kāna lawe. Loaʻa ke komo o ka mea i loko o ka ʻōpū liʻiliʻi. ʻO kekahi mau pathologies ke alakaʻi i kahi hōʻemi o ka pono o nā ʻōpū, ʻo ka hopena o ke komo ʻana o folacin ma o nā enterosit i loko o ke kōkō e iho ana. Kū ka Hypovitaminosis i ke kumu o ka maʻi o Crohn, colitis ulcerative.
- Ma muli o ka disbiosis. ʻO kekahi o nā pūhui e hana ʻia e ka microflora ʻōpū. Ma hope o ka hoʻolōʻihi ʻia ʻana o ka lāʻau antibiotic a i ʻole ka maʻi ma mua, e hoʻopilikia ʻia paha ke kaulike o nā microorganism pono, a, no laila, e emi ka hana ʻana o ka mea.
Hōʻike ʻia ka hemahema o ka huaʻai B9 e ka hana hewa ʻana i ka hematopoiesis ma ke ʻano meemia megaloblastic. Me kahi maʻi, ʻike ʻia nā hunaola koko nunui o nā megaloblast i ke koko e kūʻē i ke kumu o ka hoʻemi maʻamau o ka helu o nā erythrocytes maʻamau. Hele pū ke ʻano pathological me ka luhi wikiwiki, ka haunaele o ka noho, ka gastric achilia, ke ʻano o ka hōʻole i nā kīʻaha ʻai, ka hoʻomohala ʻia ʻana o ke alelo atrophic o Hunter - he nui o nā ʻōuli, me nā ʻano ʻoluʻolu ʻole o ke kino muscular, kahi loli o ka ʻono a me ka helehelena o ka membrane mucous e like me "alelo lacquered". ʻO ka hopena o ka holomua o ka maʻi he myelosis funicular, kahi i hōʻike ʻia e ka hele ʻole ʻana, ka helehelena o nā ʻalolo ʻoluʻolu ʻole ma ka ʻili o ka ʻili, nāwaliwali a hoʻemi i ka ʻike o nā lālā.
ʻO ka hoʻoliʻiliʻi hoʻoliʻiliʻi o ka folic acid e alakaʻi aku ai i ka hele mua o ke oho hina, nā maʻi noʻonoʻo, a me nā hāʻule ʻole.
I ke kenekulia 21, ʻano nui loa ka hypovitaminosis. Loaʻa kēia i ka hoʻomaikaʻi ākea i ka maikaʻi o ke ola. ʻO ka hōʻailona no ka lawe ʻana i ka wikamina B9 ka pale ʻana i ka malformation fetal i ka wā hāpai, a me ka hemahema i ʻike ʻia o ka hui.
Hoʻolālā ʻo Hypervitaminosis me ka overdose vitamina. I kēia hihia, hōʻino i nā puʻupaʻa, ʻōnaehana ʻōnaehana, gastrointestinal tract ia l. Hoʻohui ʻia, hōʻike nui nā kukuna kiʻekiʻe o folacin i nā noiʻi maʻi i ka hoʻemi ʻana i ka hana o nā hunaola NK, nā huna kanaka kūlohelohe o ka ʻōnaehana paleʻea. Hōʻike kēia mau mea o ka pale o ke kino i kahi hopena antitumor, no laila, hoʻonui ka hypervitaminosis i ka makaʻu o ka ulu ʻana i ka maʻi ʻaʻai.
ʻO kahi contraindication i ka hoʻohana ʻana o folacin he therapy me cytostatics a i ʻole anticonvulsants, a me ka hoʻomanawanui ʻole o kēlā me kēia i nā ʻāpana o ka lāʻau.
Ka launa pū me nā mea ʻē aʻe
Hoʻopili ka Folic acid i ka hana o nā lāʻau cytostatic. ʻO ka lunamakaʻāinana maʻamau o kēia pūʻulu pharmacological ʻo Methotrexate. Hana ka ʻākena i ka hoʻokaʻawale wikiwiki ʻana i nā hunaola, hoʻoliʻiliʻi i ka hana o nā hunaola pale. Kau ʻia ka lāʻau no ka mālama ʻana i ka maʻi ʻaʻai a me nā pathology ʻē aʻe. Hoʻokumu ʻia ka hana o ka hana ma ka hana hewa ʻana i ka metabolism folic acid, a, no laila, ʻo ka hōʻemi o ka hana o ka mahele o ka cell atypical. ʻO ka lawelawe like ʻana o Methotrexate me nā pae vitamin B9 ka hopena antitumor. No laila, maikaʻi ʻole ka launa ʻole folic me nā cytostatics.
Hoʻohana ʻia kekahi mau lāʻau e pale a mālama i ka malaria i ka folate metabolism o ka pathogen. No laila, i ka wā o ka mālama ʻana, ʻaʻohe koi ʻia i ka manawa like o kahi lāʻau a me kahi lāʻau, akā naʻe, ma hope o kahi papa o ka therapy, pono e hoʻopiha hou ʻia ka hemahema o ka hui.
Lawe i ka anticonvulsant therapy i ke alo o ka epilepsy a i ʻole nā maʻi noʻonoʻo e hōʻemi i ka paʻa o folacin.
B9 no nā kāne
Ma lalo o ka mana o ka folacin, he nui nā hopena metabolic o nā pākeke, nā momona a me nā protein i kū, he mea nui ia no nā kāne e pili ana i nā haʻuki.
Hoʻopili ka Vitamin B9 i ka hana o ka ʻōnaehana hopohopo. ʻO ka hemahema o ka mea e alakaʻi ai i ka hoʻonui ʻana i ka luhi, ka huhū, a me nā maʻi kaumaha. Hiki i kahi kāne ke hōʻike i ka huhū e kūʻē i ka hope o ka nele o ka wikamina.
Ma ka hoʻonui ʻana i ka hana o nā huna kanaka kūlohelohe, pale ka folacin i nā maʻi viral a me ke kūkulu ʻia ʻana o nā hunaola malignant atypical.
Me ka hoʻomaka ʻana o ka wā ʻōpio i nā keikikāne, pili ka waikawa folic i ke kaʻina o ka spermatogenesis, ka mea e pono ai ka hana maʻamau o ka ʻōnaehana hānau.
Folic acid no nā wahine
ʻO ka maʻa mau o ka folate i mea nui no nā wahine. I ka wā o ka hoʻolālā hāpai ʻana, paipai nā kauka e lawe i kahi hoʻokolohua koko no ka nui o ka vitamina. Hiki i kahi hemahema ke alakaʻi i ka hāʻule ʻole. Ma ke ʻano he prophylaxis no nā pathologies o ka hānau ʻana i kahi keiki, kuhikuhi nā gynecologists i ka waikawa folic ke hiki mai ka hāpai ʻana, ʻoiai ʻo ka wahine ma kahi kūlana e pono iā 200 mcg hou aku folacin. Lawe ʻia ka lāʻau e like me nā kuhikuhi. Kūlike ʻole i ka hilinaʻi kaulana e pili ana i ka palekana o nā wikamina, hiki i ka overdose ke alakaʻi i nā hopena i makemake ʻole ʻia. Aia ka manawa o ka hoʻohana ʻana i ka paʻakikī i ka pae o ka folacin i ke koko.
Ua ʻike ʻia kahi noiʻi 2005-2007 BioCycle ʻo nā wahine i loaʻa ka meaʻai kūpono o ka huaʻai B9 i hoʻemi ʻia ka makaʻu o ka anovulation ma muli o ka hoʻonui kūpono o ka hormone progesterone. I ka manawa like, hoʻonui ka nui o folacin i ke serum o nā wahine postmenopausal e hoʻonui i nā makaʻu o ka ulu ʻana i ka maʻi ʻaʻai umauma, ʻoiai ke emi nei ka hana o nā hunaola kūlohelohe.
Noi i nā haʻuki
Hoʻohana ʻia ka Vitamin B9 i nā haʻuki ʻoihana no:
- Hana paʻa o hematopoiesis. ʻO ka helu maʻamau o nā hunaola ʻulaʻula e hoʻopiha hou i nā koi o ka oxygen kikoola, e pale ana i ka hypoxia, ma muli o ka hopena o nā hana metabolic nui, me ka ulu ʻana o nā mākala.
- Hoʻonui i ka hana lolo, mālama i ke olakino olakino.
- ʻO ka maʻamau o ka hana o ka digestive tract.
- E hakakā i ka luhi. Lawe i nā pilikia i loaʻa i ka waikawa folic e ʻae iā ʻoe e wikiwiki i nā kaʻina hana o ka hoʻoponopono kino ma hope o ka hoʻoikaika ʻana i ke kino.
Nānā pinepine nā mea haʻuki ʻoihana i ka ʻike o ka wikamina B9 i loko o ke koko, ʻoiai ʻo ka nele o ka mea i hiki ke alakaʻi i kahi hōʻemi o ka hoʻomaʻamaʻa hana a me ka hōʻino ʻana i nā hopena hoʻokūkū.
Nā hiʻohiʻona Slimming
Ma muli o ka wikiwiki o ka folic acid i ka haki ʻana o nā haʻalako a me nā momona, hoʻohana ʻia ia no ka lilo wikiwiki wikiwiki ʻana. Eia naʻe, ʻaʻole lawe ka folacin wale i nā hopena i ʻike ʻia. ʻO ka mea mua, paipai nā kauka e hana i kahi hoʻokolohua olakino laulā e ʻike ai i nā kumu o ka loaʻa waiwai keu. Inā ʻo ka mea etiological nui kahi nohona noho a me ka meaʻai maikaʻi ʻole, e kuhikuhi ka loea, i ka hoʻohui ʻana i nā ana nui, ka lawe ʻana o ka wikamina B9. ʻO ka mea huna i ka lilo ʻana o ka paona ke waiho nei i ka hoʻopau ʻana i ke kumu o ka waiho nui ʻana o ke kaumaha, a me kahi ala i hoʻohui ʻia.