ʻO nā protein nā mea nui o ke kino o ke kanaka, pili lākou i ka synthesis o nā hormones a me nā enzyme, pono no ka hoʻokō ʻana i kahi helu nui o nā hopena biochemical. Kūkulu ʻia nā mole mole protein mai nā amino acid.
ʻO Leucine kekahi o nā mea nui i kēia hui. E kuhikuhi i nā amino acid pono i hiki ʻole i ke kino ke synthesize iā ia iho, akā loaʻa mai ka waho. Hoʻohana ʻia ʻo Leucine i ka meaʻai haʻuki, ka lāʻau, a me ka mahiʻai. I ka ʻoihana meaʻai, ʻike ʻia ʻo ia ka mea hoʻohui E641 L-Leucine a hoʻohana ʻia e hoʻololi i ka ʻono a me ka pilau o nā meaʻai.
ʻImi noiʻi ʻakika
No ka manawa mua, ua kaʻawale ka leucine a ua wehewehe ʻia kāna ʻano hana e ka mea kemika ʻo Henri Braconneau i ka makahiki 1820. I ka hoʻomaka o ke kenekulia 20, ua hiki iā Hermann Emil Fischer ke synthesize i kēia hui. I ka makahiki 2007, ua paʻi ka puke pai Diabetes i nā hopena o kahi noiʻi ʻepekema i nā hana a me nā waiwai o leucine. Hiki iā ʻoe ke ʻike i nā hopena a me nā hopena o ka ʻepekema e ka loulou (hōʻike ʻia ka ʻike i ka ʻōlelo Pelekania).
Lawe ʻia ka hoʻokolohua ma nā iole keʻena hoʻokolohua. Ua mahele ʻia nā holoholona i ʻelua hui. I ka mua o lākou, ua loaʻa nā ʻaʻa i nā meaʻai maʻamau, a i ka papa o ka lua ua ʻoi aku ka nui o nā meaʻai momona. I ka manawa, ua hoʻokaʻawale ʻia kēlā me kēia hui i nā ʻāpana: i kekahi o lākou, hāʻawi ʻia nā holoholona i ka 55 mg o ka leucine i kēlā me kēia lā, a i ka lua, ʻaʻole i loaʻa nā ʻiole i nā hui i hoʻohui ʻia me ka papa kuhikuhi
Wahi a nā hopena o 15 mau pule, ua hoʻololi ʻia nā holoholona i hānai ʻia me nā mea momona. Eia naʻe, ʻo ka poʻe i loaʻa nā leucine hou aʻe, ua loaʻa iā 25% ka liʻiliʻi ma mua o ka poʻe i loaʻa ʻole ka amino acid i kā lākou papaʻai.
Hoʻohui ʻia, ua hōʻike ʻia nā anamanaʻo i lawe ʻia e nā holoholona e lawe ana i ka leucine he nui aku ka oxygen ma mua o kekahi. ʻO kēia ka wikiwiki o kā lākou hana metabolic, a ʻoi aku ka nui o nā calorie i puhi ʻia. Ua hōʻike ʻia ka ʻoiaʻiʻo i nā ʻepekema e hoʻolohi ka amino acid i ke kaʻina o ka hōʻiliʻili ʻana o ka momona o ke kino.
Ua hōʻike nā ʻimi noiʻi a Laboratory o nā mākala a me nā adiposit i ke kino adipose keʻokeʻo i ka lawe ʻia ʻana o nā leucine i loko o ke kino e hoʻoulu ai i ka hana ʻana o kahi pūnaehana protein protein e hoʻonāukiuki i ka momona momona i ka pae cellular.
I ka 2009, ua hana hou nā ʻepekema mai ke Kulanui o Pennsylvania i ka hoʻokolohua a kā lākou mau hoa. Hiki ke loaʻa nā hopena o kēia noi ma aneʻi (hāʻawi ʻia ka ʻike i ka ʻōlelo Pelekania). Ua hōʻoiaʻiʻo ʻia nā hopena a nā ʻepekema. Ua ʻike ʻia nō hoʻi i ka lawe ʻana i ka huina nui o ka amino acid ʻaʻohe hopena i nāʻiole.
ʻO ke kuleana olaola o leucine
He mea nui ʻo Leucine i nā hana he nui. Hana ia i kēia mau hana:
- lohi i nā hana catabolic i nā mākala;
- hōʻeleu i ka synthesive o nā mole mole, e kōkua i ke kūkulu ʻana i ka nui o nā mākala;
- hoʻohaʻahaʻa i ke kō kō;
- hāʻawi i ke kaulike o ka nitrogen a me nā hui nitrogenous, kahi mea e pono ai no ka protein a me ka carbohydrate metabolism;
- pale i ka synthesin o ka serotonin nui, kahi e kōkua ai e hōʻemi i ka luhi a hoʻonui i ka hoʻihoʻi ʻana mai ke kaumaha.
ʻO ka ʻike maʻamau o ka leucine i loko o ke koko e hoʻoikaika i ka ʻōnaehana paleʻoniʻoni, paipai i ka hōʻeha ʻana o ka ʻeha, a me ka hōʻeleu i ke ola ʻana mai nā ʻeha. Hoʻohana ke kino iā ia ma ke ʻano he ikehu.
Noi i nā haʻuki
Me ka hoʻoikaika kino hoʻoikaika kino, pono ke kino i nā mea hou aku e kūkulu i nā olonā i nā mākala a huki i ka ikehu. I nā haʻuki, ʻo ia hoʻi ka hoʻomaʻamaʻa ikaika e like me ke bodybuilding, hāpai uila, crossfit, leucine kahi hana maʻamau.
Pono pono e hōʻemi i ka ikaika o ka catabolism a me ka wikiwiki i nā kaʻina anabolic. ʻO ka maʻamau, lawe ʻia ka amino acid i ke ʻano o ke kākoʻo haʻuki e paʻa ana kahi mānoanoa BCAA. Loaʻa iā ia ʻekolu mau amino acid pono - leucine, isoleucine a me valine.
I loko o ia mau mea hoʻopihapiha papaʻai, ʻo ka lakio o nā ʻāpana he 2: 1: 1 (pakahi, leucine, kona isomer a me valine), hoʻonui kekahi mau mea hana i ka ʻike o ka mea i hala e ʻelua a i ʻole ʻehā mau manawa.
Hoʻohana ʻia kēia amino acid e nā poʻe haʻuki no ke kūkulu ʻana i nā mākala a me ka pohō kaumaha. Hoʻohui, hoʻonui ka leucine supplementation i ka ikehu e pono ai e hoʻomaikaʻi i ka hana pāʻani.
Noi i ka lāʻau
Hoʻohana ʻia nā hoʻomākaukau leucine me nā hoʻomākaukau no ka lāʻau therapeutic. Kau ʻia lākou no nā maʻi akepaʻa nui, dystrophy, poliomyelitis, neuritis, anemia, a me kekahi mau maʻi olakino noʻonoʻo.
Ma ke ʻano he rula, hoʻopili ʻia ka hoʻokele o kēia hui me nā lāʻau i loaʻa ka glutamic acid a me nā amino acid e hoʻonui ai i ka hopena therapeutic.
ʻO nā pōmaikaʻi o ka leucine no ke kino e hoʻopili i nā hopena aʻe:
- normalization o ka hana hepatosit;
- ka hoʻoikaika ʻana i ka palekana;
- hoʻemi i ka makaʻu o ka momona;
- kākoʻo no ka ulu pono ʻana o nā mākala;
- hoʻonui o ka hoʻōla ma hope o ka hoʻoikaika kino, hoʻonui i ka pono;
- hopena maikaʻi i ke kūlana o ka ʻili.
Hoʻohana ʻia ka amino acid no ka hoʻōla hou ʻana i nā mea maʻi e ʻeha nei mai ka dystrophy, kuhikuhi ʻia ia ma hope o ka hoʻolōʻihi hoʻolōʻihi ʻana. Hoʻohana ʻia ia i ka mālama ʻana i nā maʻi ʻaʻai a me nā mea maʻi me ka cirrhosis ate. Hoʻohana ʻia lākou e hoʻolalelale i ke ola ʻana mai nā ʻeha, nā hana ʻoki, a me nā papahana anti-kūnewa.
Koina o kēlā me kēia lā
ʻO ka pono no kahi mākua he 4-6 g o ka leucine i kēlā me kēia lā. Koi aku nā mea pāʻani i nā mea hou o kēia hui.
- Inā kūkulu ka pahuhopu i ke kūkulu ʻana i nā mākala, a laila pono ia e lawe i 5-10 mau māka i ka wā a ma hope o ka hoʻomaʻamaʻa ʻana. Mālama kēia regimen i nā pae leucine i loko o ke koko i ka wā o ka hoʻoikaika kino ʻana, kahi e hōʻoia ai i ka hoʻokumu paʻa ʻana o nā mākala paʻa.
- Inā he pahuhopu ka pahuhopu o ka mea haʻuki, hoʻomaloʻo, a laila pono ʻoe e hoʻohana i nā mea hoʻopihapiha i loaʻa ka leucine 2-4 mau manawa i ka lā, i kahi nui ma kahi o 15 g. Lawe ʻia ka waihona i ka wā a ma hope o ka hoʻomaʻamaʻa ʻana, a ʻo 1-2 mau manawa hoʻi i ka lā ma waena o nā meaʻai. Hoʻoulu kēia kumumanaʻo i ka metabolism a paipai i ka puhi ʻana i ka momona. I ka manawa like, mālama ʻia ka nui o nā mākala, a kāohi ʻia nā kaʻina catabolic.
Hiki ke alakaʻi i ka maʻamau i ka leucine nui i ke kino a hōʻeha i ke olakino. He ʻōlelo aʻoaʻo e nīnau aku i ke kauka ma mua o ka hoʻohana ʻana i nā lāʻau a i ʻole nā mea hoʻopili meaʻai i loko o kēia amino acid. Hiki i nā poʻe haʻuki ke hilinaʻi i ka mea hoʻomaʻamaʻa ʻoihana ʻike e ʻike i ke ana kūpono.
ʻO nā hopena o kahi hemahema a ʻoi aku i ke kino o ka leucine
ʻO Leucine kahi amino acid pono: no laila, he mea nui ia e lawa i kēia hui mai waho. ʻO kona nele i ke kino e alakaʻi i kahi kaulike nitrogen maikaʻi ʻole a hoʻohiolo i ka papa o nā hana metabolic.
Hoʻokumu ka hemahema Leucine i ka ulu ulu ʻana o nā keiki ma muli o ka lawa ʻole o ka hana ʻana o ka hormone ulu. Eia kekahi, hoʻonāukiuki ka nele o kēia amino acid i ka ulu ʻana o hypoglycemia. Hoʻomaka nā loli pathological i nā puʻupaʻa, kelepaʻi thyroid.
Hiki ke alakaʻi i kahi leucine nui i nā pilikia like ʻole. Hāʻawi ka nui o ka lawe ʻana o kēia amino acid i ka hoʻomohala ʻana i nā ʻano pathological aʻe:
- nā maʻi neurological;
- mokuʻāina hoʻohaʻahaʻa;
- ʻeha poʻo poʻo;
- hypoglycemia;
- hoʻomohala i nā hopena maikaʻi ʻole o ke kino;
- atrophy mākala kino.
Nā Kumuwaiwai Mea Leucine
Loaʻa ke kino i kēia amino acid mai ka meaʻai a i ʻole nā mea hoʻopiha a me nā lāʻau lapaʻau - he mea nui e hōʻoia i kahi lako kūpono o kēia hui.
ʻO kekahi o nā leucine kumukanawai
E hana i kēia, ua ʻōlelo ʻia e hoʻohana i nā huahana aʻe:
- nā nati;
- soy;
- peas, legume, peanuts;
- nā paʻi paʻi (cheddar, parmesan, Switzerland, poshekhonsky);
- nā huahana waiū a me ka waiū holoʻokoʻa;
- Kuleke;
- kaviara ʻulaʻula;
- iʻa (herring, salmon pink, bass kai, mackerel, pike perch, pike, cod, pollock);
- pipi a me ka ʻiʻo bipi;
- moa moa;
- keiki hipa;
- hua moa;
- cereals (millet, corn, brown rice);
- sesame;
- heʻe;
- pauka hua manu.
Loaʻa ʻo Leucine i nā concentrates protein a me nā mea kaʻawale i hoʻohana ʻia e nā mea haʻuki.
Nā Kūʻai Kūʻai
ʻO kekahi mau anomalies hereditary rare ʻole he contraindications i ka lawe ʻana i ka leucine.
- ʻO Leucinosis (maʻi Menkes) kahi maʻi metabolic congenital o nā hydrophobic amino acid (leucine, isoleucine a me valine). ʻIke ʻia kēia pathology i nā lā mua o ke ola. Pono ka maʻi i ke koho ʻia o kahi papaʻai kūikawā, kahi e kāpae ʻia ai nā meaʻai protein. Ua hoʻololi ʻia e nā protein hydrolysates, i nele i ka BCAA amino acid complex. ʻO kahi hōʻailona o ka leucinosis kahi ʻala kikoʻī o ka mimi, kahi mea e hoʻomanaʻo ai i ke ʻala o ke kō i kuni ʻia a i ʻole ka maple syrup.
- Hāʻawi ʻia kahi kiʻi olakino e like me ka maʻi maʻi Menkes e kekahi maʻi i hoʻoholo ʻia genetically - isovaleratacidemia. He maʻi kaʻawale kēia o ka leucine metabolism, kahi e kāpae ʻia ai ka lawe ʻana o kēia amino acid i loko o ke kino.
ʻAʻole hiki i nā hopena biochemical he nui ke kino ke ʻole ka leucine. Hiki ke kiʻi ʻia mai nā huahana meaʻai i ka nui i koi ʻia me ka papaʻai kaulike wale nō, akā naʻe, me ka hoʻoikaika kino ikaika, hoʻonui nui ka ʻai ʻana o nā amino acid.
He mea nui ka lawe ʻana i ka leucine no ka poʻe ʻimi e ʻimi nei e hōʻeleu i ke kūkulu ʻana i nā mākala ma o ka hōʻemi ʻana i ka helu o nā kaʻina catabolic. ʻO ka lawe ʻana i ka amino acid e kōkua iā ʻoe e lilo i kaupaona ʻoiai e mālama ʻole ana i ka nui o nā mākala.
